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Related Experiment Video

Updated: Jul 16, 2025

Imaging Membrane Potential with Two Types of Genetically Encoded Fluorescent Voltage Sensors

Imaging Membrane Potential with Two Types of Genetically Encoded Fluorescent Voltage Sensors

Published on: February 4, 2016

DNA-Based Near-Infrared Voltage Sensors.

Giovanni Giammanco¹, Remi Veneziano^1,2, Bryce Dunn¹

¹Department of Bioengineering, George Mason University, Fairfax, Virginia 22030, United States.

|September 19, 2023

Summary

This summary is machine-generated.

Researchers developed a DNA-based nanosensor using indocyanine green (ICG) dye to overcome limitations in fluorescence imaging. This novel platform enhances ICG

Area of Science:

Biomedical Engineering
Nanotechnology
Molecular Imaging

Background:

Indocyanine green (ICG) is an FDA-approved dye for fluorescence imaging but suffers from aggregation, nonspecific targeting, and photobleaching.

Keywords:

DNA nanoparticle DNA nanotechnology DNA scaffold indocyanine green (ICG)nanosensor voltage sensing whole cell patch clamp

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Existing ICG formulations present challenges for precise cellular imaging and diagnostics.