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Updated: Jul 16, 2025

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Imaging Membrane Potential with Two Types of Genetically Encoded Fluorescent Voltage Sensors
Published on: February 4, 2016
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DNA-Based Near-Infrared Voltage Sensors
Giovanni Giammanco1, Remi Veneziano1,2, Bryce Dunn1
1Department of Bioengineering, George Mason University, Fairfax, Virginia 22030, United States.
ACS Sensors
|September 19, 2023
Summary
Researchers developed a DNA-based nanosensor using indocyanine green (ICG) dye to overcome limitations in fluorescence imaging. This novel platform enhances ICG
Area of Science:
- Biomedical Engineering
- Nanotechnology
- Molecular Imaging
Background:
- Indocyanine green (ICG) is an FDA-approved dye for fluorescence imaging but suffers from aggregation, nonspecific targeting, and photobleaching.
- Existing ICG formulations present challenges for precise cellular imaging and diagnostics.

