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Infections in Asymptomatic Unaccompanied Asylum-seeking Children in London 2016-2022
Sarah Eisen1,2, Bhanu Williams3, Jonathan Cohen4
1From the Department of Paediatrics, UCLH Hospitals NHS Foundation Trust, London, United Kingdom.
Insights
Routine screening for infections in unaccompanied asylum-seeking children found high rates of tuberculosis and schistosomiasis. This data supports regular asymptomatic infection screening for this vulnerable group.
Area of Science:
- Public Health
- Infectious Diseases
- Pediatrics
Background:
- Unaccompanied asylum-seeking children face higher infection risks and healthcare barriers.
- Limited evidence exists for asymptomatic infection screening guidelines in this population.
- This study addresses the need for data on infection prevalence in this cohort.
Purpose of the Study:
- To report on the prevalence of infections identified through routine screening.
- To provide evidence supporting the need for targeted infection screening in unaccompanied asylum-seeking children.
- To contribute to the largest dataset on infection screening in this population in Europe.
Main Methods:
- Retrospective analysis of routinely collected data.
- Screening data from 1104 unaccompanied asylum-seeking children across 3 London centers (2016-2022).
- All participants accepted voluntary infection screening.
Main Results:
- 37% of children had at least one infection; 11% had multiple infections.
- Tuberculosis (18%) and schistosomiasis (17%) were highly prevalent.
- Hepatitis B (3.9%), Giardia (7.7%), tapeworm (3.3%), and Strongyloides (2.8%) were also commonly identified.
Conclusions:
- The study presents the largest known dataset of infection screening in asymptomatic unaccompanied asylum-seeking children in Europe.
- Findings demonstrate a significant prevalence of infections of personal and public health importance.
- Data supports recommendations for routine asymptomatic screening in this high-risk population.
Background:
Unaccompanied asylum-seeking children are at increased risk of infections and experience barriers to healthcare access. There is a lack of evidence to underpin existing national and international guidance regarding asymptomatic infection screening in this population. We describe the results from routine infection screening of 1104 unaccompanied asylum-seeking children attending for testing at 3 London centers.
Methods:
We performed a retrospective analysis of routinely collected data from all unaccompanied asylum-seeking children seen in 3 services in London, United Kingdom, between 2016 and 2022.
Results:
A total of 1104 unaccompanied asylum-seeking children attended clinic; all accepted screening. The median age was 16 years (range 11-18 years) and 987 (89%) were male. 407 (37%) had at least 1 infection; 116 (11%) had multiple infections. Tuberculosis infection and schistosomiasis were common (found in 18% and 17%, respectively). Hepatitis B infection was identified with a prevalence of 3.9%. Giardia 7.7%, tapeworm 3.3% and Strongyloides 2.8% were also commonly identified.
Conclusions:
We report the largest known dataset to our knowledge of infection screening in asymptomatic unaccompanied asylum-seeking children in Europe to date. This data supports recommendations for routine asymptomatic screening in this high-risk cohort, based on the significant prevalence identified of infections of both personal and public health significance.
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