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Related Experiment Videos

Quantities of amino acids ingested by human milk-fed infants.

L M Janas, M F Picciano

    The Journal of Pediatrics
    |November 1, 1986
    PubMed
    Summary

    Infant amino acid intake from human milk decreases significantly with age. By 8 weeks, intakes for most essential amino acids fall below recommended levels, suggesting current requirements may be overestimated.

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    Area of Science:

    • Nutritional Science
    • Pediatric Nutrition
    • Human Milk Composition

    Background:

    • Accurate assessment of infant nutrient intake is crucial for growth and development.
    • Human milk is the primary source of nutrition for many infants.
    • Established requirements for essential amino acids guide infant feeding practices.

    Purpose of the Study:

    • To quantify amino acid intake in human milk-fed infants.
    • To compare infant amino acid consumption with established Food and Agriculture Organization/World Health Organization (FAO/WHO) requirements.
    • To identify potential discrepancies in recommended amino acid intakes.

    Main Methods:

    • Studied ten term infants fed human milk ad libitum at 2, 4, and 8 weeks of age.
    • Measured milk volume intake.
    • Performed amino acid analysis on human milk samples.

    Main Results:

    • Total amino acid and nitrogen intake decreased by approximately 34% from 2 to 8 weeks.
    • This decline was linked to a 20% decrease in milk amino acid concentrations.
    • At 8 weeks, mean intake for seven of nine essential amino acids fell below FAO/WHO recommended levels.

    Conclusions:

    • Infant amino acid intake from human milk declines significantly with age.
    • Current FAO/WHO estimates for several essential amino acids may be overestimated.
    • Further research is needed to refine amino acid requirements for human milk-fed infants.

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