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The Role of Anatomical Dissection in Defining Colic and Small Bowel Artery Lymphovascular Bundles in the D3 Volume of Small and Large Bowel Mesentery
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The Role of Anatomical Dissection in Defining Colic and Small Bowel Artery Lymphovascular Bundles in the D3 Volume of Small and Large Bowel Mesentery

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Intussusception due to lymphoma

S H Ein, C A Stephens, B Shandling

    Journal of Pediatric Surgery
    |September 1, 1986
    PubMed

    Insights

    Lymphoma is a rare cause of intussusception in children, accounting for 17% of pathological lesions. Despite treatment, survival rates are low, but some children have had long-term success with chemotherapy or radiotherapy.

    Area of Science:

    • Pediatric Surgery
    • Pediatric Oncology
    • Gastroenterology

    Background:

    • Intussusception is a common surgical emergency in infants and children.
    • Lymphoma as a leading point for intussusception is a rare occurrence.
    • Identifying malignancy in children with intussusception is crucial for appropriate management.

    Purpose of the Study:

    • To investigate the incidence and outcomes of intussusception caused by lymphoma in children.
    • To analyze the clinical presentation, diagnostic methods, and treatment strategies for these cases.
    • To evaluate the long-term survival rates and prognostic factors.

    Main Methods:

    • Retrospective review of pediatric intussusception cases over 40 years.
    • Analysis of clinical data, including age, symptoms, diagnostic imaging (barium studies), and treatment modalities.
    • Correlation of pathological findings with clinical outcomes.

    Main Results:

    • Eleven cases of intussusception with lymphoma as the leading point were identified (17% of pathological lesions).
    • Most affected children presented with chronic symptoms, weight loss, and abdominal masses, suggesting malignancy.
    • Hydrostatic barium enema achieved reduction in 10 of 11 patients, but surgery confirmed lymphoma requiring resection.
    • Despite aggressive treatment, mortality was high, with only 3 survivors.

    Conclusions:

    • Childhood intussusception due to lymphoma is rare but associated with a poor prognosis.
    • Early suspicion of malignancy is vital in children with prolonged intussusception symptoms.
    • Multimodal treatment including surgery, chemotherapy, and radiotherapy may offer long-term survival in select cases.

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