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Nonpharmacological Interventions to Reduce Sedation and General Anesthesia in Pediatric MRI: A Meta-analysis

Jakob Thestrup1, Jane Hybschmann1, Thurid W Madsen2

  • 1Juliane Marie Centre and Mary Elizabeth's Hospital.

Hospital Pediatrics
|September 20, 2023
PubMed
Abstract

Insights

Nonpharmacological interventions significantly reduce the need for sedation and general anesthesia in pediatric MRI scans. These strategies should be standard practice for infants, children, and adolescents undergoing MRI.

Area of Science:

  • Pediatric Radiology
  • Medical Imaging
  • Interventional Radiology

Background:

  • Pediatric MRI often requires sedation or general anesthesia.
  • Nonpharmacological strategies are gaining traction in pediatric procedures.

Purpose of the Study:

  • To assess nonpharmacological interventions for reducing sedation/anesthesia in pediatric MRI.
  • To evaluate impacts on scan time, image quality, and patient anxiety.

Main Methods:

  • Systematic review and meta-analysis of 46 eligible studies.
  • Included randomized controlled trials and quasi-experimental designs.
  • Searched major databases (Ovid Medline, CINAHL, Embase, CENTRAL) up to October 2022.

Main Results:

  • Nonpharmacological interventions reduced sedation/anesthesia needs in pediatric MRI (RR 0.68 RCTs, 0.58 non-RCTs).
  • The effect was most pronounced in children aged 3-10 years.
  • Significant heterogeneity was noted in nonrandomized studies.

Conclusions:

  • Nonpharmacological interventions are effective in decreasing sedation/anesthesia use during pediatric MRI.
  • These methods should be integrated as standard care for pediatric MRI patients.
  • Further research may address heterogeneity in nonrandomized study designs.

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