Related Experiment Video
Updated: Jul 16, 2025
08:05
Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice
Published on: June 29, 2022
2.8K
Abnormal Atrial Potentials Recorded During Sinus Rhythm or Pacing Represent Substrates for Reentrant Atrial
Yosuke Nakatani1,2, F Daniel Ramirez1,2,3,4, Masateru Takigawa1,2
1Department of Cardiac Pacing and Electrophysiology, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, France (Y.N., F.D.R., M.T., T.N., C.A., C.G., P.K., T.T., T.K., V.K., G.C., R.T., N.W., R.C., J.D., T.P., N.D., F.S., M. Hocini, M. Haïssaguerre, P.J.).
Circulation. Arrhythmia and Electrophysiology
|September 20, 2023
Summary
Abnormal atrial potentials (AAPs) during sinus rhythm predict slow conduction zones in atrial tachycardia (AT) circuits. AAP mapping offers insights into AT pathways, aiding diagnosis in complex cases.
Area of Science:
- Electrophysiology
- Cardiac Arrhythmias
- Atrial Tachycardia
Background:
- Abnormal atrial potentials (AAPs) during sinus rhythm or atrial pacing may signify slow conduction areas.
- These slow conduction areas are capable of sustaining reentrant atrial tachycardia (AT).
Purpose of the Study:
- To investigate the correlation between AAPs identified during sinus rhythm/atrial pacing and the circuits of reentrant AT.
- To determine if AAP characteristics can predict AT circuit features.
Main Methods:
- Analysis of 123 reentrant ATs from 104 patients.
- Assessment of AAPs, including fragmented and split potentials, using the Rhythmia LUMIPOINT algorithm.
Main Results:
- Significant overlap (93±13%) was observed between AAP areas and slow conduction zones within AT circuits.
- Localized-reentrant ATs showed smaller AAP areas compared to anatomic macro-reentrant ATs.
- AAP distribution varied with AT type (perimitral, roof-dependent) and scar characteristics.
Conclusions:
- AAPs recorded during sinus rhythm/atrial pacing are linked to slow conduction areas in reentrant AT circuits.
- The extent and location of AAPs provide valuable information about AT circuit properties.
- AAP mapping can aid in understanding and diagnosing AT, especially in challenging cases.
Related Concept Videos
01:29Dysrhythmias III: Characteristics of Dysrhythmias
12
Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per...
12
01:28Dysrhythmias II: Classification of Tachyarrhythmias
11
Tachyarrhythmias are a type of dysrhythmia where the heart rate exceeds 100 beats per minute. Here are some common types of tachyarrhythmias:Sinus TachycardiaSinus tachycardia originates from increased impulses from the sinus node, leading to an elevated heart rate. It is often triggered by stress, fever, or exercise.Patients may experience palpitations, a sensation of a racing heart, dizziness, and chest discomfort.Causes and Risk Factors: Common causes include physical exertion, emotional...
11
01:28Mechanism of Cardiac Arrhythmias
950
Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
950
01:25ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
40
Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
40
01:28Disturbances in Heart Rhythm
1.0K
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
1.0K
01:18Dysrhythmias IV: Characteristics of Bradyarrhythmias
11
Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
11