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Related Concept Videos

SBAR II: Application of SBAR01:14

SBAR II: Application of SBAR

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SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
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A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS
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Harmonized standard operating procedures for administering the ALS functional rating scale-revised.

Jeremy M Shefner1, Tommy Bunte2, Gale Kittle1

  • 1Department of Neurology, Barrow Neurological Institute, Phoenix, AZ, USA.

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration
|September 20, 2023
PubMed
Summary
This summary is machine-generated.

Standardizing training for the ALS Functional Rating Scale-Revised (ALSFRS-R) is crucial for reliable clinical trial outcomes. This study introduces a harmonized procedure to ensure consistent ALSFRS-R training across North America and Europe, reducing response variability.

Keywords:
ALSFRS-RClinical trialtraining

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Area of Science:

  • Neurology
  • Clinical Trials
  • Outcome Measurement

Background:

  • The ALS Functional Rating Scale-Revised (ALSFRS-R) is the primary outcome measure in amyotrophic lateral sclerosis (ALS) clinical trials.
  • Training and certification are vital for reliable ALSFRS-R performance.
  • Discrepancies exist in current ALSFRS-R training protocols between major training groups.

Purpose of the Study:

  • To present a harmonized standard operating procedure for ALSFRS-R training.
  • To reduce response variability in ALS clinical trials through standardized training.
  • To ensure identical ALSFRS-R training across North America and Europe.

Main Methods:

  • Development of a harmonized standard operating procedure for ALSFRS-R training.
  • Implementation of identical training protocols in North America and Europe.
  • Focus on reducing inter-rater and intra-rater variability in ALSFRS-R assessments.

Main Results:

  • The harmonized procedure aims to minimize differences in training.
  • Anticipated reduction in response variability for the ALSFRS-R.
  • Facilitation of more consistent data collection in multi-center ALS trials.

Conclusions:

  • A unified ALSFRS-R training approach is essential for enhancing the reliability of clinical trial data.
  • The harmonized standard operating procedure offers a pathway to more consistent and comparable ALS clinical trial outcomes.
  • Standardization of ALSFRS-R training is key to advancing ALS research and therapeutic development.