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Published on: April 19, 2021
The Effect of Benzyl Alcohol on the Voltage-Current Characteristics of Tethered Lipid Bilayers
Hadeel Alobeedallah1, Bruce Cornell2, Mohammed Ghazal3
1Department of Electrical, Computer and Biomedical Engineering, Abu Dhabi University, Abu Dhabi, United Arab Emirates. haal5646@uni.sydney.edu.au.
Abstract:
In this study a lipid bilayer membrane model was used in which the bilayer is tethered to a solid substrate with molecular tethers. Voltage-current (V-I) measurements of the tethered bilayer membranes (tBLM) and tBLM with benzyl alcohol (BZA) incorporated in their structures, were measured using triangular voltage ramps of 0-500 mV. The temperature dependence of the conductance deduced from the V-I measurements are described. An evaluation of the activation energies for electrical conductance showed that BZA decreased the activation/ Born energies for ionic conduction of tethered lipid membranes. It is concluded that BZA increased the average pore radius of the tBLM.
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