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Predicting ciprofloxacin and levofloxacin decomposition utilizing ozone micro-nano bubbles through the central
Yasser Babaee1, Seyed Fazlolah Saghravani1, Javad Feizy2
1Faculty of Civil Engineering, Shahrood University of Technology, Shahrood, Iran.
Environmental Technology
|September 20, 2023
Summary
Ozone micro-nano bubbles effectively remove antibiotics like ciprofloxacin and levofloxacin from water. This advanced oxidation process offers a promising solution for treating pharmaceutical contaminants in aquatic environments.
Area of Science:
- Environmental Chemistry
- Water Treatment Technologies
Background:
- Antibiotics pose significant risks to aquatic ecosystems.
- Conventional water treatment methods struggle to degrade pharmaceutical pollutants.
- Advanced oxidation processes are needed for effective antibiotic removal.
Purpose of the Study:
- To investigate the efficacy of ozone micro-nano bubbles (OzMNBs) for degrading ciprofloxacin (CIPR) and levofloxacin (LEVO).
- To optimize the decomposition process by analyzing key variables like pH, ozonation time, and initial antibiotic concentration.
Main Methods:
- Utilized central composite design for experimental optimization.
- Employed Design Expert software (version 13.0.1) for quadratic model analysis.
- Conducted verification tests to confirm optimal decomposition conditions.
Main Results:
- Optimal conditions determined as pH 9, 40 minutes ozonation, and 5 mg/L initial concentration.
- Achieved high removal rates: approximately 97% for CIPR and 100% for LEVO.
- Identified the influence of factors and their interactions on antibiotic decomposition.
Conclusions:
- OzMNBs demonstrate high efficiency in removing CIPR and LEVO from aqueous solutions.
- The study provides optimized parameters for antibiotic degradation using OzMNBs.
- Further research examined the removal of total organic carbon and mineralization, indicating broader water purification potential.

