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Updated: Jul 16, 2025

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats
Published on: March 8, 2019
Surgery and Anesthesia in Patients with Pulmonary Hypertension
Robin Condliffe1,2, Ruth Newton3, Kris Bauchmuller4
1Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, United Kingdom.
Surgery for pulmonary hypertension is complex due to right ventricular impairment. Careful patient selection and multidisciplinary management optimize outcomes for this challenging patient group.
Area of Science:
- Cardiology
- Anesthesiology
- Thoracic Surgery
Background:
- Pulmonary hypertension (PH) causes right ventricular (RV) dysfunction, complicating surgical procedures.
- Despite challenges, surgical intervention for PH is increasingly feasible due to targeted therapies and better long-term survival.
- Managing PH patients undergoing surgery necessitates a comprehensive, team-based approach.
Purpose of the Study:
- To outline the optimal management pathway for patients with pulmonary hypertension undergoing surgery.
- To emphasize the importance of a multidisciplinary approach in achieving favorable surgical outcomes for PH patients.
Main Methods:
- Risk:benefit analysis for surgical procedures in PH patients.
- Preoperative optimization of pulmonary hypertension and comorbidities.
- Tailored anesthetic strategies based on patient and procedure specifics.
- Close postoperative monitoring and management.
Main Results:
- Careful patient selection is crucial for successful surgical outcomes.
- Meticulous perioperative management significantly impacts patient recovery.
- Multidisciplinary collaboration enhances the safety and efficacy of surgical interventions in PH.
Conclusions:
- Surgical management of pulmonary hypertension can yield good outcomes when patients are carefully selected and meticulously managed.
- A coordinated, multidisciplinary approach is essential for optimizing care and improving survival in PH patients undergoing surgery.
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08:34Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
Published on: November 18, 2018
07:02A Large Animal Model for Pulmonary Hypertension and Right Ventricular Failure: Left Pulmonary Artery Ligation and Progressive Main Pulmonary Artery Banding in Sheep
Published on: July 15, 2021
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