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Related Concept Videos

Potentiometry: Overview01:06

Potentiometry: Overview

2.2K
Potentiometry is an analytical technique that measures the potential difference between two electrodes in an electrochemical cell without drawing any significant current that could alter the solution's composition. This method employs an indicator electrode, which exchanges electrons with the analyte solution, and a reference electrode with a constant potential. Each electrode is immersed in a solution comprised of two half-cells. In a conventional setup, the reference electrode serves as...
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Potentiometry: Membrane Electrodes01:15

Potentiometry: Membrane Electrodes

623
Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at...
623
Controlled-Potential Coulometry: Electrolytic Methods01:17

Controlled-Potential Coulometry: Electrolytic Methods

197
Controlled-potential coulometry, also known as potentiostatic coulometry, employs a three-electrode system in which the working electrode's potential is precisely regulated using a potentiostat. Platinum working electrodes are utilized for positive potentials, while mercury pool electrodes are favored for extremely negative potentials. The platinum counter electrode is separated from the analyte using a membrane or salt bridge to avoid interference in the analysis.
The chosen potential...
197
Potentiometry: Types of Electrodes01:19

Potentiometry: Types of Electrodes

723
Reference electrodes serve as a stable reference point for potentiometric measurements, while indicator and working electrodes react to variations in the composition of a solution.
The Standard Hydrogen Electrode (SHE) is a widely used reference electrode that maintains zero potential across all temperatures. However, its need for a continuous hydrogen gas supply renders it impractical for everyday use.
An alternative to SHE is the Saturated Calomel Electrode (SCE). This electrode features an...
723
Interfacial Electrochemical Methods: Overview01:06

Interfacial Electrochemical Methods: Overview

280
Interfacial electrochemical methods focus on the phenomena occurring at the boundary between an electrode and a solution, as opposed to bulk methods that concentrate on the solution's overall properties. These interfacial methods are classified as either static or dynamic based on the presence of a nonzero current in the electrochemical cell and the consistency of analyte concentrations. Static methods, such as potentiometry, measure the cell's potential without any significant current...
280
Potentiometric Titration: Overview01:31

Potentiometric Titration: Overview

1.5K
Potentiometric titration is a quantitative analytical technique that determines the concentration of an analyte by measuring the potential difference between the two electrodes in the solution. The endpoint of a potentiometric titration is the point at which there is a significant change in the potential difference. It occurs when the stoichiometric reaction between the analyte and the titrant is complete. The endpoint is usually determined graphically by plotting the measured potential...
1.5K

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Modern Potentiometric Biosensing Based on Non-Equilibrium Measurement Techniques.

Junsong Mou1,2, Jiawang Ding1,3, Wei Qin1,3

  • 1CAS Key Laboratory of Coastal Environmental Processes, and Ecological Remediation, Shandong Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS), Yantai, 264003, Shandong, P. R. China.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|September 21, 2023
PubMed
Summary

Recent advances in potentiometric biosensors utilize polymeric membrane ion-selective electrodes (ISEs) and non-equilibrium techniques. Combining these with artificial intelligence (AI) enhances data processing for improved sensing capabilities.

Keywords:
bioreceptorsdynamic responsesmachine learningnon-equilibrium measurementspotentiometric biosensing

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Area of Science:

  • Electrochemistry
  • Biosensing
  • Sensor Technology

Background:

  • Polymeric membrane ion-selective electrodes (ISEs) have advanced significantly in sensitivity, selectivity, and stability.
  • Nonclassical potentiometry and dynamic measurement approaches offer new avenues for potentiometric biosensing.
  • Applications span environmental surveillance, medical diagnostics, and industrial analysis.

Purpose of the Study:

  • To summarize a decade of progress in potentiometric biosensors using polymeric membrane ISEs.
  • To articulate sensing mechanisms based on non-equilibrium measurement techniques.
  • To highlight the integration of ISEs with artificial intelligence (AI) for enhanced data processing.

Main Methods:

  • Focus on non-equilibrium measurement techniques and dynamic approaches in potentiometric biosensing.
  • Review of representative examples illustrating applications under zero-current and stimulus-controlled conditions.
  • Discussion on the synergy between ISEs and AI for effective data analysis.

Main Results:

  • Non-equilibrium measurements provide dynamic responses yielding valuable information.
  • Dynamic approaches in potentiometric biosensing demonstrate significant potential.
  • Integration with AI offers advanced data processing capabilities for ISEs.

Conclusions:

  • Non-equilibrium measurement techniques and dynamic approaches present vast possibilities in potentiometric biosensing.
  • The combination of ISEs with AI techniques is crucial for effective data processing and future innovation.
  • This field holds great promise for continued advancements in sensing technologies.