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Updated: Jul 16, 2025

Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes
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Strong structuring arising from weak cooperative O-H···π and C-H···O hydrogen bonding in benzene-methanol solution

Camilla Di Mino1, Andrew G Seel2, Adam J Clancy3

  • 1Department of Physics and Astronomy, University College London, London, WC1E 6BT, UK.

Nature Communications
|September 22, 2023
PubMed
Summary

Weak hydrogen bonds, like O-H···π and C-H···O, guide molecular interactions. This study reveals how these bonds create ordered structures in liquid benzene-methanol mixtures, observed using neutron diffraction.

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