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Genetic Lingo

Genetic Lingo

Pedigree Analysis

Pedigree Analysis

Incomplete Dominance

Incomplete Dominance

Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.

Law of Segregation

Law of Segregation

When crossing pea plants, Mendel noticed that one of the parental traits would sometimes disappear in the first generation of offspring, called the F1 generation, and could reappear in the next generation (F2). He concluded that one of the traits must be dominant over the other, thereby causing masking of one trait in the F1 generation. When he crossed the F1 plants, he found that 75% of the offspring in the F2 generation had the dominant phenotype, while 25% had the recessive phenotype.

Test Cross

Test Cross

Alleles are different forms of the same gene. Humans and other diploid organisms inherit two alleles of every gene, one from each parent.

Probability Laws

Probability Laws

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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

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Goldilocks principle and recessive disease

Alexandre Fabre^1,2, Paul Guerry³

¹APHM, Timone Enfant, Service de pédiatrie multidisciplinaire, Marseille, France. alexandre.fabre@ap-hm.fr.

European Journal of Human Genetics : EJHG

|September 22, 2023

Summary

No abstract available in PubMed .

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