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Published on: November 6, 2019
The efficacy of perioperative antibiotic therapy in adenotonsillectomy children
Ying Wang1, Limin Zhao1, Jing Wang1
1Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, No.355, Luding Road, Shanghai, 200062, People's Republic of China.
Insights
Perioperative antibiotics in children undergoing adenotonsillectomy effectively reduced postoperative fever and throat pain, shortening recovery time. This intervention is particularly beneficial for patients with higher tonsillar bed grading, indicating improved outcomes.
Area of Science:
- Pediatric Otolaryngology
- Pharmacology
- Surgical Outcomes
Background:
- Adenotonsillectomy is a common pediatric surgical procedure.
- Postoperative pain and fever are significant concerns following adenotonsillectomy.
- The role of perioperative antibiotics in managing these outcomes requires further clarification.
Purpose of the Study:
- To evaluate the efficacy of perioperative antibiotic use in children after adenotonsillectomy.
- To assess the impact on postoperative pain, diet resumption, and wound healing.
- To identify risk factors associated with postoperative complications.
Main Methods:
- Statistical analysis using SPSS 27.0.
- Independent samples t-tests for pain scores, diet resumption, and wound healing.
- Logistic regression and generalized estimation models to identify risk factors and correlations.
Main Results:
- The observation group (with perioperative antibiotics) showed significantly lower pain scores on days 1-3 post-surgery compared to the control group.
- Pain duration was shorter in the observation group (6.24 days vs. 7.73 days).
- Fever was identified as an independent risk factor negatively correlated with antibiotic use (OR=0.290). Age and tonsillar bed grading positively correlated with pain scores.
Conclusions:
- Perioperative antibiotics are effective in reducing postoperative fever and throat pain in children after adenotonsillectomy.
- Antibiotic therapy is more crucial for patients with higher tonsillar bed grading.
- The findings support the use of perioperative antibiotics to improve recovery after adenotonsillectomy.
Purpose:
To evaluate the role of perioperative antibiotics use in children after adenotonsillectomy.
Methods:
SPSS 27.0 was used for statistical analysis. Two independent samples mean T test was used to evaluate the throat pain scores consecutive 3 days after the surgery, the time to resume to normal diet, and the wound healing time. Logistic regression analysis was used to evaluate the independent risk factors of the two groups. The generalized estimation model was used to evaluate the correlation between age and postoperative pain scores, and the relationship between different tonsillar bed gradings and postoperative pain scores.
Results:
The pain scores were 5.83 ± 1.879, 5.20 ± 1.933, and 4.02 ± 1.936 in the observation group; and 6.83 ± 1.892, 6.17 ± 2.001, and 5.29 ± 2.068 in the control group on days 1-3 after surgery, respectively. The time of pain disappearance was 6.24 ± 2.121 days in the observation group and 7.73 ± 2.210 days in the control group. The wound repair time was 18.66 ± 2.200 days in the observation group and 18.70 ± 2.468 days in the control group. Logistic regression analysis showed that fever was an independent risk factor for the two groups and was negatively correlated (B = - 1.237, P < 0.001, OR = 0.290). Generalized estimation model showed that there was a positive correlation between age and pain scores (P < 0.001), and with the increasing grading of tonsillar bed, the higher the pain scores was (P < 0.001).
Conclusions:
Perioperative use of antibiotics in children with adenotonsillectomy can effectively reduce postoperative fever, throat pain symptoms, and shorten the pain time. With the increasing of tonsillar bed grading, perioperative antibiotic therapy was more necessary.
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