[Myasthenia gravis and autoimmunity]

A disorder in immune system is thought to be the factor in Myasthenia gravis. Certain antibodies against various tissues have been detected in the sera of this group of patients. Anti-acetyl-cholin receptor antibodies are positive in 90% of the patients with M.G. Basic pathology is thought to be the destruction in post-synaptic membrane, resulted from the reaction in which an autoimmune response directed to acetyl-cholin receptors.