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Influence of time of day on resting motor threshold in clinical TMS practice

Karen Wendt1, Majid Memarian Sorkhabi2, Jacinta O'Shea3

  • 1MRC Brain Network Dynamics Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX1 3TH, UK; Department of Engineering Science, University of Oxford, Oxford OX1 3PJ, UK.

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
|September 22, 2023
PubMed
Abstract

No abstract available in PubMed .

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Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
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