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A single-cell atlas of CD19 chimeric antigen receptor T cells
Xubin Li1, Jared Henderson1, Max J Gordon1
1Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Cancer Cell
|September 22, 2023
Abstract:
Li et al. present a resource of single-cell RNA sequencing (scRNA-seq) data from the infusion products of relapsed or refractory large B cell lymphoma (rrLBCL) patients treated with standard-of-care axicabtagene ciloleucel and identify features that are significantly different between products from responders and non-responders at 3-month followup by PET/CT, an important landmark for long-term outcomes.
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