Related Experiment Video
Updated: Jul 16, 2025

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
A multivariable model of barriers to COVID-19 vaccination: Using cross sectional data from a nationally distributed
Francisco A Montiel Ishino1, Kevin Villalobos2, Faustine Williams2
1Division of Intramural Research, Epidemiology Branch, National Institute of Environmental Health Sciences, Durham, NC, USA.
Objective:
Discrimination has had longstanding effects on mental and physiological health, which became more evident and synergized during the COVID-19 pandemic. The role of discrimination on vaccination for COVID-19 during the pandemic, however, is not well understood. As such, we examined the relationship of everyday discrimination on COVID-19 vaccination.
Methods:
Using a multivariate logistic regression on data collected from a nationally distributed survey in the United States (US), we examined the relationship of discrimination measured by the Everyday Discrimination Scale on self-reported COVID-19 vaccination while adjusting for US nativity, as well as sociodemographic (i.e., age; gender; sexual orientation; race, and ethnicity) and socioeconomic (i.e., educational attainment; employment status; household income) factors.
Results:
We found that participants reporting monthly to weekly discrimination and multiple times a week to daily discrimination had decreased odds of reporting COVID-19 vaccination (adjusted odds ratio [AOR] = 0.78, 95% confidence interval [CI]:0.68-0.90; and AOR = 0.75, 95% CI = 0.62-0.91, respectively) compared to those that reported no discrimination experienced. Educational attainment of high school equivalent or above, employment as an essential worker, and household-annual income of $50,000 or greater were significant socioeconomic factors. Age, sexual orientation, and race/ethnicity had mixed associations with COVID-19 vaccination.
Conclusions:
Discrimination overall remained a significant barrier to vaccination, while nativity was not significant when accounting for socioeconomic and sociodemographic factors. Discrimination must become a public health priority in addressing disparities in health and access and barriers that may affect preventive behaviors.
Related Concept Videos
Contingency Table
Bias in Epidemiological Studies
Statistical Methods for Analyzing Epidemiological Data
Cross-Sectional Research
Confounding in Epidemiological Studies
Model Approaches for Pharmacokinetic Data: Compartment Models
Two primary types of compartment models are recognized: mammillary and catenary. The more...

