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Neuropathic changes in corneal nerve endings-A potential objective biomarker for migraine frequency and response to

Nur Amalina Md Isa1, Shyam S Tummanapalli1, Jeremy Chung Bo Chiang1,2

  • 1School of Optometry and Vision Science, University of New South Wales, Sydney, New South Wales, Australia.

Headache
|September 23, 2023
PubMed
Abstract

No abstract available in PubMed .

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Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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