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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Updated: Jul 16, 2025

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
03:35

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

331

Obesity: a gender-view.

G Muscogiuri1,2,3, L Verde4,5, C Vetrani4,6

  • 1Dipartimento Di Medicina Clinica E Chirurgia, Diabetologia E Andrologia, Unità Di Endocrinologia, Università Degli Studi Di Napoli Federico II, Via Sergio Pansini 5, 80131, Naples, Italy. giovanna.muscogiuri@gmail.com.

Journal of Endocrinological Investigation
|September 23, 2023
PubMed
Summary
This summary is machine-generated.

Gender significantly impacts obesity, affecting body fat distribution and treatment responses. Understanding these differences is crucial for effective obesity management and drug development.

Keywords:
Body compositionDietGenderObesityWeight loss drugs

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Area of Science:

  • Endocrinology
  • Pharmacology
  • Public Health

Background:

  • Obesity prevalence and characteristics exhibit gender-specific patterns.
  • Understanding gender differences is vital for effective obesity management.

Purpose of the Study:

  • To review current evidence on anthropometric, nutritional, and pharmacological aspects of obesity from a gender perspective.
  • To highlight the importance of gender in obesity research and treatment.

Main Methods:

  • Literature search conducted within PubMed.
  • Selected publications on obesity and gender differences were reviewed.

Main Results:

  • Women have higher body fat percentage and different obesity phenotypes (gynoid vs. android).
  • Gender-specific analysis is uncommon in anti-obesity drug trials, despite potential pharmacokinetic/pharmacodynamic differences.
  • Bariatric surgery shows gender disparities in outcomes and psychological challenges.

Conclusions:

  • Gender is a critical variable in obesity prevalence, phenotype, and body fat distribution.
  • Differences exist in drug efficacy, clinical trial representation, and bariatric surgery outcomes based on gender.
  • Further research is needed to address gender-specific responses to obesity treatments.