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Updated: Jul 16, 2025
Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
Published on: September 7, 2022
INFECTIOUS MONONUCLEOSIS DURING THE WAR AND COVID INFECTION PANDEMIC IN UKRAINE
Kateryna Pikul1, Valentine Ilchenko1, Liudmyla Syzova1
1POLTAVA STATE MEDICAL UNIVERSITY, POLTAVA, UKRAINE.
Insights
Infectious mononucleosis in children is a growing concern in Ukraine, with a 5% increase in incidence observed between 2009 and 2022. While Poltava shows lower rates, overall trends warrant attention for pediatric infectious disease management.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Infectious mononucleosis, often caused by Epstein-Barr virus, is a common childhood illness.
- Understanding its incidence and management is crucial for public health.
- Current diagnostic and management strategies require ongoing analysis.
Purpose of the Study:
- To analyze current perspectives on diagnosing and managing infectious mononucleosis in children.
- To conduct a comparative analysis of infectious mononucleosis incidence in Ukraine and Poltava from 2006 to 2022.
Main Methods:
- Bibliosemantic analysis of scientific literature.
- Retrospective analysis of statistical data on infectious mononucleosis incidence (2006-2022).
- Analysis of common pediatric infectious pathologies (2019-2022) and vaccination coverage.
Main Results:
- Infectious mononucleosis incidence in children showed an increase in 2009, stabilizing between 23-25.2 per 100,000 children in subsequent years.
- The Poltava region reported one of the lowest incidence rates in Ukraine (8.1-10.1% over the last 3 years).
- Lower reported rates in Poltava may be linked to reduced hospital visits during COVID-19 and lower regional COVID-19 rates.
Conclusions:
- The overall spread of infectious mononucleosis in Ukrainian children is concerning.
- A 5% increase in incidence was noted between 2009 and 2022.
- Continued monitoring and updated management strategies are essential for pediatric infectious mononucleosis.
Objective:
The aim: To analyze the current views on diagnosis and management of infectious mononucleosis in children. The purpose of our work is also a comparative characteristic of the incidence of infectious mononucleosis in Ukraine and the city of Poltava (2006-2022).
Patients And Methods:
Materials and methods: The data of scientific literature have been analyzed, using the bibliosemantic method of study. We used a retrospective analysis of statistical data on the incidence of infectious mononucleosis 2006-2022 and the most frequent cases of infectious pathology in children in the period 2019- 2022, and also conducted an analysis of the percentage of those vaccinated according to the vaccination calendar.
Results:
Results: We had an increase in the incidence in 2009, but in subsequent years it was in the range of 23-25.2 per 100.000 children. The incidence of patients diagnosed with infectious mononucleosis per 100.000 of the children population in the Poltava region is one of the lowest in Ukraine, accounting for 8.1 - 10.1% over the past 3 years, which can be explained by the decrease in visits by parents and their children to the hospital to avoid contact with patients with the coronavirus disease and the fact that our region also had rather lower rates of children with Covid-19 compared in Ukraine.
Conclusion:
Conclusions: the situation with the spread of infectious mononucleosis in children in Ukraine is such that it causes concern, and when comparing the incidence in 2009 and 2022, the authors noted an increase in the overall incidence of this nosology by 5%.
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