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Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
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Rules and mechanisms governing G protein coupling selectivity of GPCRs

Ikuo Masuho1, Ryoji Kise2, Pablo Gainza3

  • 1Department of Neuroscience, UF Scripps Biomedical Research, Jupiter, FL 33458, USA; Pediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, SD 57104, USA; Department of Pediatrics, Sanford School of Medicine, University of South Dakota, Sioux Falls, SD 57105, USA.

Cell Reports
|September 24, 2023
PubMed

Keywords:
BRET assayCP: Cell biologyG proteinGEF activityGPCRGαclassificationgenetic variationsignaling biassystems biology

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