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Potentially Inappropriate Prescribing in Long-Term Care and its Relationship With Probable Delirium.

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Potentially inappropriate prescribing (PIP) is common in long-term care. Higher instances of PIP significantly increase the risk of probable delirium among residents.

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Area of Science:

  • Geriatric Medicine
  • Pharmacology
  • Public Health

Background:

  • Potentially inappropriate prescribing (PIP) is a significant concern in long-term care (LTC) settings.
  • Delirium is a common and serious condition in older adults residing in LTC facilities.

Purpose of the Study:

  • To investigate the prevalence of PIP in Ontario LTC residents.
  • To examine the association between PIP and probable delirium in this population.

Main Methods:

  • Population-based cross-sectional study utilizing provincial health administrative and LTC assessment data (RAI-MDS 2.0).
  • PIP assessed using STOPP/START and Beers criteria; probable delirium identified via Clinical Assessment Protocol.
  • Logistic regression models used to analyze the relationship between PIP and delirium.

Main Results:

  • Over half of 171,190 LTC residents exhibited PIP (51.8% by STOPP/START).
  • Prevalence of probable delirium increased with higher numbers of PIP instances.
  • Residents with 3+ instances of PIP were 1.66 times more likely to have probable delirium.

Conclusions:

  • PIP is highly prevalent among LTC residents in Ontario.
  • A significant association exists between PIP and an increased prevalence of probable delirium.
  • Central nervous system-related PIP criteria demonstrated a stronger link to delirium.