Baclofen pseudopsychosis: case report.

Area of Science:

• Neurology
• Pharmacology
• Psychiatry

Background:

• Baclofen, a muscle relaxant, is known to cause hallucinations upon sudden withdrawal.
• Previous literature has not documented persistent hallucinations during long-term baclofen therapy responsive to dosage adjustments.

Observation:

• A case is presented of a patient experiencing chronic hallucinations.
• These symptoms were initially misdiagnosed as a psychotic illness.

Findings:

• The patient's hallucinations persisted for several years while on baclofen treatment.
• A reduction in baclofen dosage led to the resolution of the chronic hallucinations.
• This suggests baclofen toxicity can manifest as persistent hallucinations.

Implications:

• This case expands the understanding of baclofen's potential side effects beyond acute withdrawal.
• It highlights the importance of considering medication toxicity in chronic, unexplained psychiatric symptoms.
• Further research into long-term baclofen toxicity and management is warranted.