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Engineering RsDddA as mitochondrial base editor with wide target compatibility and enhanced activity

Kai Cheng1, Cao Li1, Jiachuan Jin2

  • 1State Key Laboratory of Reproductive Medicine, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.

Molecular Therapy. Nucleic Acids
|September 25, 2023
PubMed

Keywords:
DdCBEMT: RNA/DNA Editingbase editingmitochondrial diseasemtDNA engineeringtarget compatibility

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