Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

High serum bile acid level in obesity: its decrease during and after total fasting.

L Halmy, T Fehér, K Steczek

    Acta Medica Hungarica
    |January 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Sub-nanosecond heat-based logic, writing and reset in an antiferromagnetic magnetoresistive memory.

    PhotoniX·2025
    Same author

    Correction to: The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival.

    Cell death and differentiation·2025
    Same author

    Effect of non-spherical shape of dry powder aerosol drugs on their airway deposition distribution.

    International journal of pharmaceutics·2025
    Same author

    Fast neutron generation with few-cycle, relativistic laser pulses at 1 Hz repetition rate.

    Scientific reports·2024
    Same author

    Large shallow lake response to anthropogenic stressors and climate change: Missing macroinvertebrate recovery after oligotrophication (Lake Balaton, East-Central Europe).

    The Science of the total environment·2024
    Same author

    Feasibility of individualised patient modelling for continuous vancomycin infusions in outpatient antimicrobial therapy, a retrospective study.

    International journal of clinical pharmacy·2023
    Same journal

    Cisplatin containing combination chemotherapy of advanced germ cell line testicular tumours.

    Acta medica Hungarica·1994
    Same journal

    Cytokines in the treatment of malignancies.

    Acta medica Hungarica·1994
    Same journal

    Osteoporosis--a modifying factor of surgical treatment.

    Acta medica Hungarica·1994
    Same journal

    New aspects in the treatment of bone sarcomas.

    Acta medica Hungarica·1994
    Same journal

    Bone tumours in childhood.

    Acta medica Hungarica·1994
    Same journal

    Lymphadenectomy in gastrointestinal cancer surgery.

    Acta medica Hungarica·1994
    See all related articles

    Fasting for 14 days reduced elevated serum bile acid levels in overweight individuals to normal ranges. Bile acid levels remained stable after refeeding, suggesting fasting aids bile acid homeostasis in obesity.

    Area of Science:

    • Metabolic disorders
    • Gastroenterology
    • Endocrinology

    Background:

    • Obesity is linked to elevated serum bile acid levels.
    • Bile acid dysregulation is implicated in metabolic dysfunction.

    Purpose of the Study:

    • To investigate the effect of fasting on serum bile acid concentrations in overweight individuals.
    • To assess the impact of refeeding on bile acid homeostasis after fasting.

    Main Methods:

    • Serum bile acid levels (cholic, chenodeoxycholic, deoxycholic) were measured in overweight subjects.
    • Subjects underwent a 14-day fasting period.
    • Serum bile acid levels were monitored during a subsequent 2-day refeeding period.

    Main Results:

    Related Experiment Videos

  • Overweight subjects exhibited higher serum bile acid levels compared to normal weight individuals.
  • Fasting for 14 days led to a significant decrease in serum bile acid concentrations, normalizing them.
  • Serum bile acid levels did not change significantly during the 2-day refeeding period.

    • Conclusions:

    • Fasting effectively normalizes elevated serum bile acid levels in overweight individuals.
    • Bile acid homeostasis can be restored through fasting, independent of weight reduction.
    • These findings highlight fasting as a potential therapeutic strategy for managing bile acid dysregulation in obesity.