Malignus emlőtumor? Gyulladásos emlőelváltozás? Ritka benignus kórkép?

Area of Science:

• Oncology
• Pathology
• Dermatology

Background:

• Rosai-Dorfman disease (RDD) is a rare, benign histiocytosis typically affecting lymph nodes but can involve extranodal sites.
• Breast involvement in RDD is exceptionally rare and can clinically resemble breast cancer.

Observation:

• A 58-year-old female presented with a breast mass and multiple cutaneous lesions, initially suspected as malignant breast cancer with metastasis.
• Initial biopsies (core and excisional) were insufficient for a definitive diagnosis.

Findings:

• Complete pathological examination of the surgically excised breast lesion led to the correct diagnosis of Rosai-Dorfman disease.
• The case highlights the diagnostic challenges posed by extranodal RDD, particularly in the breast.

Implications:

• This case underscores the importance of comprehensive pathological evaluation for rare breast conditions.
• Accurate diagnosis of Rosai-Dorfman disease is crucial for appropriate patient management and avoiding misdiagnosis as malignancy.