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Elevated serum TARC levels precede classic Hodgkin lymphoma diagnosis by several years
Arjan Diepstra1, Ilja M Nolte2, Anke van den Berg1
1Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Abstract:
Tumor cells in classic Hodgkin lymphoma produce high quantities of the thymus- and activation-related chemokine (TARC). We measured TARC levels in prediagnostic serum samples and found strikingly increased values in the vast majority of patients, as early as 6 years before diagnosis.
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