Introducing "Rapid phage susceptibility testing" (RPST): an accelerated lytic phage activity test for routine
R Skusa1, J Kohlen1, A Podbielski1
1Institute of Medical Microbiology, Virology and Hygiene, University Medicine Rostock, Rostock, Germany.
Diagnostic Microbiology and Infectious Disease
|September 25, 2023
Abstract:
Phage therapy, particularly for infections due to multi-drug-resistant bacteria, is increasingly gaining in importance. Consecutively, there is a rising need for phage testing in routine diagnostic laboratories. The incubation time of phage susceptibility testing for detecting lytic phage activity on phage/host strain combinations was evaluated. A standardized approach for routine diagnostic laboratories provided reliably detectable lysis zones within 8 hours.


