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Updated: Jul 15, 2025

Assessment of Bone Fracture Healing Using Micro-Computed Tomography
Published on: December 9, 2022
Computed Tomography Bone Imaging: Pushing the Boundaries in Clinical Practice
Romain Gillet1,2,3, Fatma Boubaker1, Gabriela Hossu2,3
1Guilloz Imaging Department, Central Hospital, University Hospital Center of Nancy, Nancy, France.
Abstract:
Bone microarchitecture has several clinical implications over and above estimating bone strength. Computed tomography (CT) analysis mainly uses high-resolution peripheral quantitative CT and micro-CT, research imaging techniques, most often limited to peripheral skeleton assessment. Ultra-high-resolution (UHR) CT and photon-counting detector CT, two commercially available techniques, provide images that can approach the spatial resolution of the trabeculae, bringing bone microarchitecture analysis into clinical practice and improving depiction of bone vascularization, tumor matrix, and cortical and periosteal bone. This review presents bone microarchitecture anatomy, principles of analysis, reference measurements, and an update on the performance and potential clinical applications of these new CT techniques. We also share our clinical experience and technical considerations using an UHR-CT device.
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