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[The relation between antimycobacterial activity and complex formation of various compounds]
Die Pharmazie
|July 1, 1986
Abstract:
Analytic agents were tested from the point of view of their antimycobacterial effect. It was found, that substances forming complexes with Cu-ions, namely dithiocarbamates and their oxidation products, show very high antimycobacterial activity. Small stability of the dithiocarbamates in acidic medium leads to the tests, the aim of which was to replace these substances with chemically stable, but antimycobacterially active compounds. Dibenzoyldisulfide was found as one of these substances.