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Related Concept Videos

Sulfur Assimilation01:20

Sulfur Assimilation

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Sulfur is an essential element in biological systems, contributing to synthesizing key biomolecules, including amino acids such as cysteine and methionine, and cofactors such as coenzyme A and biotin. Microorganisms primarily assimilate sulfur as sulfate (SO₄²⁻) from the environment, which must undergo a series of biochemical transformations before it can be incorporated into cellular components. As sulfate is highly oxidized, it must undergo assimilatory sulfate reduction to...
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Vitamins01:30

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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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Labeling DNA Probes03:31

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
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Role of Vitamins in Maintaining Bone Health01:25

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
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Updated: Jul 15, 2025

In Vitro Biochemical Assays using Biotin Labels to Study Protein-Nucleic Acid Interactions
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In Vitro Biochemical Assays using Biotin Labels to Study Protein-Nucleic Acid Interactions

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Biotin.

Monice Fiume1, Wilma F Bergfeld2, Donald V Belsito2

  • 1Cosmetic Ingredient Review Senior Director.

International Journal of Toxicology
|September 26, 2023
PubMed
Summary
This summary is machine-generated.

The Expert Panel for Cosmetic Ingredient Safety reaffirmed that Biotin is safe for cosmetic use. Updated reviews confirm its safety in current product types, concentrations, and usage frequencies.

Keywords:
BiotinCosmeticsSafety

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Area of Science:

  • Cosmetic Science
  • Dermatology
  • Toxicology

Background:

  • Biotin, a B vitamin, is widely used in cosmetic products.
  • Previous safety assessments for cosmetic ingredients are periodically updated.

Purpose of the Study:

  • To review updated information on Biotin's safety as a cosmetic ingredient.
  • To reassess Biotin's safety based on current product usage patterns.

Main Methods:

  • The Expert Panel for Cosmetic Ingredient Safety reviewed updated scientific literature.
  • Evaluated current product types, usage frequency, and ingredient concentrations.

Main Results:

  • Updated information confirmed the safety of Biotin.
  • Current practices of use and concentrations are consistent with safety.

Conclusions:

  • Biotin is safe for use as a cosmetic ingredient.
  • The original safety conclusion from 2001 is reaffirmed.