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Updated: Jul 15, 2025

Cellular Redox Profiling Using High-content Microscopy
Published on: May 14, 2017
bubbleHeatmap: an R package for visualization of nightingale health metabolomics datasets
Ruth Boxall1,2, Michael V Holmes1,2, Robin G Walters1,2
1Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Summary:
We present bubbleHeatmap, an R plotting package which combines elements of a bubble plot and heatmap to conveniently display two numerical variables for each data point across a categorical two dimensional grid. This has particular advantages for visualizing the 251 metabolomic measures produced by the automated, high-throughput, 1H-NMR-based platform provided by Nightingale Health, which includes 12 measures repeated across each of 14 lipoprotein subclasses. As these metabolomic profiles are currently available for large biobanks, we provide a figure template to aid the use of bubbleHeatmap in displaying results from analyses using these data.
Availability And Implementation:
https://cran.r-project.org/web/packages/bubbleHeatmap.
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