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A Descriptive Analysis of Febrile Seizure Hospitalizations in Children with Congenital Heart Disease in the United
Ebenezer O Adebiyi1, Ruth Y Eletta2, William Ogedengbe3
1Pediatric Cardiology, University of Texas Health Science Center, Houston McGovern Medical School, Houston, USA.
Insights
Children with congenital heart disease (CHD) admitted for febrile seizures (FS) experienced longer hospital stays and higher costs. This underscores the need for targeted preventive strategies for this high-risk group.
Area of Science:
- Pediatric Neurology
- Cardiology
- Health Services Research
Background:
- Febrile seizure (FS) is the most common convulsive disorder in children.
- Congenital heart disease (CHD) is a significant comorbidity in pediatric populations.
- Understanding the impact of CHD on FS hospitalizations is crucial for resource allocation and patient management.
Purpose of the Study:
- To determine the national prevalence of CHD among children hospitalized for FS.
- To analyze differences in hospital resource utilization between children with and without CHD admitted for FS.
- To evaluate the association between CHD and hospital stay duration in pediatric FS admissions.
Main Methods:
- Retrospective cross-sectional analysis of the Kids Inpatient Database (KID) for 2016 and 2019.
- Inclusion of pediatric patients up to six years old with a primary diagnosis of FS.
- Comparison of demographic, hospital, and clinical characteristics using chi-square tests and linear/logistic regressions.
Main Results:
- An estimated 10,039 children were admitted for FS, with 1.2% having a CHD diagnosis.
- Children with CHD had a longer mean length of hospital stay (2.1 vs. 1.6 days) for FS.
- Hospital charges were significantly higher for children with CHD ($30,960.28 vs. $21,005.11).
Conclusions:
- Pediatric patients with CHD admitted for FS incur increased hospital stays and resource utilization.
- The findings highlight a vulnerable population requiring focused preventive care strategies.
- This research emphasizes the importance of integrated care for children with FS and concurrent CHD.
Background:
Febrile seizure (FS) is the most common convulsive disorder in children. This study analyzed the national proportion of congenital heart disease (CHD) and hospital resource utilization among children admitted for FSs in the U.S.
Methods:
This is a retrospective cross-sectional analysis of pediatric patients up to six years with a primary diagnosis of FS in 2016 and 2019 using the Kids Inpatient Database (KID). The demographic, hospital, and clinical characteristics of children with and without CHD were compared using the chi-square test for categorical variables and linear regressions for continuous variables. Multivariate logistic analysis was conducted to evaluate the impact of CHD on the mean length of hospital stay.
Results:
An estimated 10,039 children were admitted with the primary diagnosis of FS. Out of these, 117 (1.2%) had a discharge diagnosis of CHD. The mean age for children with and without CHD was 1.4 years (SD 1.60) and 1.5 years (SD 1.501), respectively. Children with CHD who required hospitalization for FS had longer mean lengths of hospital stay (2.1 days vs. 1.6 days), with an adjusted odd ratio of 0.43 (95% CI: 0.07-0.99; p-value: 0.017). Similarly, the hospital charges for children with CHD were higher than those without CHD ($30,960.28 vs. $21,005.11).
Conclusion:
Children with CHD who required inpatient admission for FSs in the U.S. were associated with increased length of hospital stay and higher resource utilization when compared with those without CHD. This highlights the need for preventive measures among this vulnerable population.
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