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Investigating Intestinal Inflammation in DSS-induced Model of IBD

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Diarrhoea: An Inflammatory Disorder Mimicking an Infection.

Usman Khan¹, Amr Elseby², Hassan Qureshi³

¹Internal Medicine, Royal Preston Hospital, Preston, GBR.

|September 26, 2023

Summary

This case study highlights Behcet's colitis, a rare cause of acute bloody diarrhea in patients with Behcet's disease. Prompt diagnosis and treatment with immunosuppressants led to a rapid recovery.

Keywords:

abdominal pain auto immune behcet's disease bloody stool diarrhoea infective inflammatory

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Chronic Salmonella Infection Induced Intestinal Fibrosis

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Area of Science:

Gastroenterology
Immunology
Internal Medicine

Background:

Diarrhoea presents multifactorial causes in acute emergencies, increasing misdiagnosis risk.
Inflammatory diseases are among the potential causes of acute diarrhoea.
Behcet's disease is a multisystemic inflammatory disorder.

Observation:

A patient with known Behcet's disease presented with acute onset bloody diarrhoea.
Gastrointestinal involvement, specifically colitis, was suspected as a manifestation of the underlying condition.
Investigations included computed tomography (CT) scan, sigmoidoscopy, and histology.

Findings:

The patient was diagnosed with Behcet's colitis, a rare gastrointestinal manifestation.
Histological examination confirmed the inflammatory nature of the colitis.
The condition was identified as part of the patient's multisystemic inflammatory disorder.

Implications:

This case underscores the importance of considering Behcet's colitis in patients with Behcet's disease presenting with gastrointestinal symptoms.
Early diagnosis and appropriate treatment, including steroids, mesalazine, and biologics like infliximab, are crucial for favorable outcomes.
Recognizing gastrointestinal manifestations of Behcet's disease can prevent diagnostic delays and improve patient management.