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Extradural contralateral S1 nerve root transfer for spastic lower limb paralysis.
Jiang Cao1, Jie Chang1, Chaoqin Wu1
1Department of Orthopedics, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.
Journal of Biomedical Research
|September 26, 2023
Summary
Transferring the S1 ventral root (VR) to the L5 VR is anatomically feasible for treating lower limb paralysis. This surgical option may restore function in patients with unilateral spastic paralysis.
Area of Science:
- Neurosurgery
- Anatomy
Background:
- Unilateral spastic lower limb paralysis presents significant mobility challenges.
- Current treatments for spastic paralysis have limitations.
- Nerve transfer techniques offer potential therapeutic strategies.
Purpose of the Study:
- To evaluate the anatomical feasibility of transferring the contralateral S1 ventral root (VR) to the ipsilateral L5 VR.
- To assess the viability of this nerve transfer for treating unilateral spastic lower limb paralysis.
Main Methods:
- Six formalin-fixed cadavers (3 male, 3 female) were utilized for anatomical assessment.
- The contralateral S1 VR was transferred to the ipsilateral L5 VR, using the sural nerve as a conduit.
- Axon counts, cross-sectional areas, and distances between nerves were measured.
Main Results:
- The S1 and L5 VRs were identifiable using anatomical landmarks.
- The gross distance between S1 and L5 nerve roots was measured.
- Axon counts and cross-sectional areas of S1 and L5 VRs were quantified.
Conclusions:
- The contralateral S1 VR to ipsilateral L5 VR transfer is anatomically feasible.
- This nerve transfer technique shows promise as a treatment for unilateral spastic lower limb paralysis.
