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Published on: January 6, 2011
[Subthalamic deep brain stimulation in a case of idiopathic Parkinson's disease and schizophrenia]
G Fernández-Pajarín1,2, B Ares-Pensado1,2, A Koukoulis3
1Hospital Clínico Universitario de Santiago, Santiago de Compostela, España.
Introduction:
Parkinson's disease (PD) and schizophrenia can coexist. Antipsychotics block striatal D2 receptors, which inevitably aggravates the manifestations of PD.
Case Report:
We report the case of a male patient with idiopathic Parkinson's disease and schizophrenia, with poor tolerance to minimal doses of levodopa, who underwent a dramatic improvement after bilateral subthalamic deep brain stimulation (DBS-STN). DBS-STN was taken into consideration here, due to the severity of this particular case, as the only possible way to achieve motor improvement.
Conclusions:
The diagnosis of idiopathic PD was confirmed despite antidopaminergic treatment. DBS-STN can be considered a treatment option for disabling manifestations of PD, provided that a careful selection of patients is carried out..
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