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Updated: Jul 15, 2025

Single-Cell Analysis of the Expression of Pseudomonas syringae Genes within the Plant Tissue
Published on: October 6, 2022
A large-scale phylogeny-guided analysis of pseudogenes in Pseudomonas aeruginosa bacterium
Nimrod Cohen1, Isana Veksler-Lublinsky1
1Department of Software and Information Systems Engineering, Faculty of Engineering, Ben-Gurion University of the Negev , Beer-Sheva, Israel.
Importance:
Accurate annotation of genes and pseudogenes is vital for comparative genomics analysis. Recent studies have shown that bacterial pseudogenes have an important role in regulatory processes and can provide insight into the evolutionary history of homologous genes or the genome as a whole. Due to pseudogenes' nature as non-functional genes, there is no commonly accepted definition of a pseudogene, which poses difficulties in verifying the annotation through experimental methods and resolving discrepancies among different annotation techniques. Our study introduces an in-depth analysis of annotated genes and pseudogenes and insights that can be incorporated into improved pseudogene annotation pipelines in the future.
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