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SpaceOAR hydrogel complications in prostate cancer
Harpreet Grewal1, Rajendra Kedar2, Gagandeep Dhillon3
1Department of Radiology, Sacred Heart Hospital, Radiology Associates of Florida, Pensacola, United States.
The British Journal of Radiology
|September 26, 2023
Summary
SpaceOAR hydrogel minimizes rectal radiation in prostate cancer patients but can cause imaging complications. This review highlights these issues for better patient management and accurate interpretation of imaging studies.
Area of Science:
- Oncology
- Radiology
- Biomaterials
Background:
- SpaceOAR hydrogel is a biodegradable spacer used in prostate cancer radiation therapy.
- It aims to reduce rectal radiation dose and associated complications.
- Concerns exist regarding its potential complications and impact on imaging interpretation.
Purpose of the Study:
- To provide a pictorial review of imaging complications associated with SpaceOAR hydrogel use in prostate cancer patients.
- To illustrate the types of complications, their mechanisms, and their impact on patient outcomes and imaging.
- To enhance radiologists' and oncologists' understanding for improved patient management.
Main Methods:
- Pictorial review of imaging findings.
- Presentation of multiple case examples.
- Discussion of underlying mechanisms and clinical impact.
Main Results:
- SpaceOAR hydrogel can lead to specific imaging complications.
- These complications can affect the interpretation of subsequent imaging studies.
- Understanding these complications is crucial for accurate diagnosis and treatment planning.
Conclusions:
- Radiologists and oncologists must be aware of SpaceOAR hydrogel-related imaging complications.
- This knowledge aids in accurate interpretation of imaging and optimal patient management.
- Further understanding improves outcomes for prostate cancer patients undergoing radiation therapy.

