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Updated: Jul 15, 2025

Author Spotlight: Alleviating Nausea and Vomiting in Pregnancy with Safe and Effective Auricular Acupuncture
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Published on: August 4, 2023

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Hyperemesis Gravidarum Causing Wernicke's Encephalopathy and Korsakoff's Psychosis: A Case Report

Tajah M Alaithan1, Lama K Alharbi1, Saba M Aldusaymani1

  • 1Medicine and Surgery, Al Maarefa University, Riyadh, SAU.

Cureus
|September 27, 2023
PubMed

Wernicke's encephalopathy (WE) is an acute neuropsychiatric emergency due to thiamine deficiency. This report includes a case of a young pregnant female in her second trimester (17th weeks) complaining of hyperemesis gravidarum, who, due to excessive vomiting, developed severe vitamin B1 deficiency, leading to WE and Korsakoff's psychosis. The typical triad of confusion, ocular signs, and ataxia is fundamental for the diagnosis of WE, yet not all cases present with the entire triad; however, our patient presented with all the symptoms. Replacement of thiamine, which is a crucial vitamin that plays an important role in the integrity of the nervous system, is the first step in the management of WE.

Keywords:
case reporthyperemesis gravidarumkorsakoff's psychosispregnancythiamine deficiencywernicke's encephalopathy

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