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Lupus Pancreatitis Masquerading as Pancreatic Cancer: A Rare Clinical Presentation
Gandhi Lanke1, Busara Songtanin2, Kanak Das1
1Division of Gastroenterology, Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX.
ACG Case Reports Journal
|September 27, 2023
Summary
Systemic lupus erythematosus (SLE) can cause pancreatitis, which may appear as cancer on imaging. Endoscopic ultrasound aids in diagnosing and managing this rare SLE complication.
Area of Science:
- Autoimmune diseases
- Gastroenterology
- Oncology
Background:
- Systemic lupus erythematosus (SLE) is a complex autoimmune disorder affecting multiple organ systems.
- Pancreatitis is an uncommon manifestation of SLE.
- Pancreatic cancer is exceedingly rare in SLE patients.
Observation:
- Imaging findings in SLE-associated pancreatitis can be mistaken for pancreatic malignancy.
- Distinguishing pancreatitis from cancer in SLE patients presents a diagnostic challenge.
Findings:
- Endoscopic ultrasound (EUS) offers detailed visualization of the pancreas.
- EUS-guided fine-needle aspiration (FNA) or biopsy provides tissue for definitive diagnosis.
- Accurate diagnosis is crucial for appropriate patient management.
Implications:
- EUS-FNA/biopsy is a valuable tool for differentiating SLE-associated pancreatitis from pancreatic cancer.
- Improved diagnostic accuracy can lead to tailored treatment strategies for SLE patients.
- This approach enhances the management of rare pancreatic complications in autoimmune diseases.
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