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COVID-19 Disease Characterization and Outcomes Comparison in Pediatrics
Rachel Rowland1,2, Abigail Schauble1,2, Brendon Cornett3
1Presbyterian St. Luke's Medical Center, Denver, CO.
HCA Healthcare Journal of Medicine
|September 27, 2023
Summary
COVID-19 in children hospitalized showed a low disease burden. Risk factors for longer hospital stays included ICU time, surgeries, and certain comorbidities like diabetes and PTSD.
Area of Science:
- Pediatric Infectious Diseases
- Epidemiology of Viral Illnesses
Background:
- Evolving understanding of COVID-19 severity in pediatric populations compared to adults.
- Need for detailed characterization of hospitalized pediatric COVID-19 cases.
Purpose of the Study:
- To characterize hospitalized pediatric COVID-19 patients.
- Assess risk factors for poor outcomes and mortality.
- Evaluate interventions and clinical outcomes.
Main Methods:
- Multi-center retrospective chart review of pediatric COVID-19 patients (≤18 years).
- Data collected from US HCA Healthcare Pediatric service lines (Jan-Nov 2020).
- Negative Binomial Regression used to analyze factors influencing length of hospital stay.
Main Results:
- Low comorbidity prevalence (2.7%) and mortality rate (0.1%) in the cohort.
- Majority of patients (93.6%) hospitalized for less than 48 hours.
- Increased length of stay associated with ICU time, surgeries, developmental disorders, diabetes, PTSD, suicidal ideation, and admission type.
Conclusions:
- Pediatric COVID-19 patients in this cohort exhibited a low baseline and hospitalization disease burden.
- Continued research is crucial to fully understand the disease course in children.
- Further studies are needed to describe COVID-19 in pediatric populations as the pandemic evolves.
Keywords:
COVID-19SARS-CoV-2adolescentbinomial regression analysischildcomorbiditycoronaviruscritical caredisease characterizationhospitalizationpandemicpediatricspharmacotherapyretrospective studiestreatment outcomesMore Related Videos
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