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Filtration

Filtration

Filtration is a physical separation process that involves passing a suspension through a porous medium to separate solids from fluids. During filtration, solids collect on the porous medium while liquids, also collectively known as the filtrate, pass through. The filtration medium is selected based on the filtration purpose, quantity, and nature of the precipitate. The general criteria for a suitable filtering medium are that it is inert, mechanically strong, nonabsorbent toward dissolved...

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Updated: Jul 15, 2025

Sample Preparation in Quartz Crystal Microbalance Measurements of Protein Adsorption and Polymer Mechanics

Sample Preparation in Quartz Crystal Microbalance Measurements of Protein Adsorption and Polymer Mechanics

Published on: January 22, 2020

Quantification of Particle Filtration Using a Quartz Crystal Microbalance Embedded in a Microfluidic Channel.

Siqi Ji¹, Ran Ran¹, Ilia Chiniforooshan Esfahani¹

¹Mechanical and Industrial Engineering, Northeastern University, Boston, Massachusetts 02115-5005, United States.

Langmuir : the ACS Journal of Surfaces and Colloids

|September 27, 2023

Summary

This study introduces a quartz crystal microbalance method for real-time colloidal filtration monitoring. It quantifies particle deposition in microfluidic channels, offering an alternative to optical methods.

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Published on: August 27, 2013

Area of Science:

Colloidal science
Microfluidics
Surface science

Background:

Colloidal filtration is crucial in various applications.
Accurate real-time monitoring of particle deposition is challenging.
Existing methods may be limited in optically opaque systems.

Purpose of the Study:

To develop and validate a novel method for quantifying colloidal filtration in microfluidic channels.
To monitor real-time particle deposition using a quartz crystal microbalance (QCM).
To investigate the influence of ionic concentration on filtration efficiency.

Main Methods:

Integration of a QCM with a silicon dioxide surface into a microfluidic channel.
Flow of potassium chloride solution with polystyrene particles simulating bacteria.
Real-time monitoring of QCM resonance frequency shifts due to particle deposition.
Analysis of particle trapping influenced by Derjaguin-Landau-Verwey-Overbeek (DLVO) forces.

Main Results:

Successful real-time quantification of micrometer-size particle deposition.
Demonstration of QCM resonance frequency shift correlating with mass increase.
Filtration efficiency was observed to be dependent on ionic concentration.
The method proved effective in an optically opaque microfluidic channel.

Conclusions:

QCM offers a viable technique for real-time colloidal filtration assessment.
This method provides an alternative for opaque microfluidic systems.
Understanding DLVO forces is key to optimizing filtration processes.