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Rapid Homogeneous Detection of Biological Assays Using Magnetic Modulation Biosensing System

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Recent Progresses in Optical Biosensors for Interleukin 6 Detection.

Marjan Majdinasab¹, Marc Lamy de la Chapelle², Jean Louis Marty³

¹Department of Food Science & Technology, School of Agriculture, Shiraz University, Shiraz 71441-65186, Iran.

|September 27, 2023

Summary

Optical biosensors offer a sensitive, rapid, and user-friendly alternative for detecting Interleukin 6 (IL-6), a key biomarker in various diseases. This review highlights advancements in optical biosensor technology for IL-6 monitoring.

Keywords:

biosensor interleukin 6 optical biosensor

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Area of Science:

Biomedical Engineering
Analytical Chemistry
Immunology

Background:

Interleukin 6 (IL-6) is a pleiotropic cytokine implicated in numerous pathological conditions, including inflammatory, infectious, and oncogenic diseases.
Accurate and sensitive detection of IL-6 is crucial for disease diagnosis and monitoring due to its role as a significant biomarker.
Conventional methods like ELISAs and CLIAs for IL-6 detection are often complex, expensive, and time-consuming.

Purpose of the Study:

To review and evaluate recent advancements in optical biosensors for the detection of Interleukin 6 (IL-6).
To compare the performance of various optical biosensor types for IL-6 monitoring.
To highlight the advantages of biosensors over traditional immunoassay techniques for IL-6 detection.

Main Methods:

Comprehensive literature review of optical biosensor technologies applied to IL-6 detection.
Evaluation of sensor sensitivity, selectivity, detection time, and ease of use.
Comparative analysis of different optical detection principles and their suitability for IL-6.

Main Results:

Optical biosensors demonstrate high sensitivity and rapid detection capabilities for IL-6.
These biosensors offer advantages in terms of simplicity, cost-effectiveness, and miniaturization compared to conventional immunoassays.
Various optical techniques show promise for developing user-friendly and efficient IL-6 monitoring tools.

Conclusions:

Optical biosensors represent a promising technological advancement for the sensitive and rapid detection of IL-6.
The development of user-friendly optical biosensors can significantly improve disease biomarker monitoring in clinical and research settings.
Further research and development in optical biosensor technology are warranted to optimize performance and facilitate widespread adoption for IL-6 analysis.