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Short Peptides for Hydrolase Supramolecular Mimicry and Their Potential Applications
Paola Alletto1,2,3, Ana Maria Garcia2,3, Silvia Marchesan1
1Chemical and Pharmaceutical Sciences Department, University of Trieste, 34127 Trieste, Italy.
Abstract:
Hydrolases are enzymes that have found numerous applications in various industrial sectors spanning from pharmaceuticals to foodstuff and beverages, consumers' products such as detergents and personal care, textiles, and even for biodiesel production and environmental bioremediation. Self-assembling and gelling short peptides have been designed for their mimicry so that their supramolecular organization leads to the creation of hydrophobic pockets for catalysis to occur. Catalytic gels of this kind can also find numerous industrial applications to address important global challenges of our time. This concise review focuses on the last 5 years of progress in this fast-paced, popular field of research with an eye towards the future.

