Related Experiment Video
Updated: Jul 15, 2025

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Current treatment approach to ANCA-associated vasculitis
1Clinical Associate Professor of Medicine, NYU Grossman School of Medicine, New York, NY, US.
Purpose Of Review:
This review will attempt to summarize the most potentially impactful new data on the way ANCA-associated vasculitis (AAV) is diagnosed, treated, and monitored.
Recent Findings:
The newly developed classification criteria for AAV have serious methodological issues that need to be addressed before they are widely adopted. The newly approved drugs and studies into both achieving remission and maintaining it have added to our overall knowledge of managing AAV and should hopefully contribute to improving outcomes in AAV.
Summary:
The diagnosis, treatment and monitoring of AAV have seen major improvements in the last two years. The remaining issues outlined in this review still need to be addressed to best serve AAV patients.
Insights
Recent advancements in diagnosing and treating ANCA-associated vasculitis (AAV) offer improved patient outcomes. However, newly proposed classification criteria require further validation before widespread adoption to ensure optimal management of AAV.
Area of Science:
- Rheumatology
- Immunology
- Internal Medicine
Background:
- ANCA-associated vasculitis (AAV) encompasses a group of rare autoimmune diseases characterized by inflammation of small blood vessels.
- Effective diagnosis, treatment, and monitoring are crucial for managing AAV and preventing organ damage.
Conclusions:
- While progress has been made, addressing the limitations of new AAV classification criteria is essential.
- Continued research and clinical application of new therapies hold promise for improving AAV patient outcomes.
- Further efforts are needed to optimize the comprehensive management of ANCA-associated vasculitis.
Related Concept Videos
Peripheral Artery Disease III: Interprofessional Care
Nephrotic Syndrome II : Assessment and Medical Management
Pericarditis III: Medical Management
Aneurysm III: Interprofessional Care
Angina IV: Management
Myocarditis III: Medical Management

