Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ethics in Research01:56

Ethics in Research

23.0K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
23.0K
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

394
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
394
Human Genetics01:28

Human Genetics

601
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
601
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

13.6K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
13.6K
Ethical Issues01:27

Ethical Issues

1.0K
Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
1.0K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

34.6K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
34.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-term Penetrance of Disease Variants in Genes Prioritized for Genomic Newborn Screening: Evidence from Adult Biobanks.

medRxiv : the preprint server for health sciences·2026
Same author

The Biobank Rare Variant consortium powers the discovery of rare genetic associations through global collaboration.

medRxiv : the preprint server for health sciences·2026
Same author

Imagining Genomics and Population Health in 2050: Anticipating Future Research, Policy, and Governance Needs.

Public health genomics·2026
Same author

Mechanism of age-related accumulation of mtDNA mutations in human blood.

Nature·2026
Same author

Systematic common and rare variant association testing in 392,030 whole genomes in <i>All of Us</i>.

medRxiv : the preprint server for health sciences·2026
Same author

Effect of ancestry and shared genetic architecture of serious mental illness on symptoms and cognition in an admixed Latin American population.

medRxiv : the preprint server for health sciences·2026
Same journal

"Wouldn't It Be Easier to Be Burned at the Stake?": Schizophrenia and Deinstitutionalization in <i>Bitter Medicine</i>.

Perspectives in biology and medicine·2026
Same journal

The Mental Health Crisis of Rural America: Understanding Supply and Demand.

Perspectives in biology and medicine·2026
Same journal

The Final Act of Care: Accuracy in Cause of Death Statements.

Perspectives in biology and medicine·2026
Same journal

Existential Competence: Redefining Clinical Excellence Beyond Health Optimization.

Perspectives in biology and medicine·2026
Same journal

Making Fun of Medicine: Resisting Medicine's Principalities.

Perspectives in biology and medicine·2026
Same journal

Courage, Conviction, Resolve: The Story of Dr. Gui Xi'en.

Perspectives in biology and medicine·2026
See all related articles

Related Experiment Video

Updated: Jul 15, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

33.8K

An Ethical Framework for Research Using Genetic Ancestry.

Anna C F Lewis, Santiago J Molina, Paul S Appelbaum

    Perspectives in Biology and Medicine
    |September 27, 2023
    PubMed
    Summary
    This summary is machine-generated.

    This study proposes a virtue ethics framework for researchers using genetic ancestry to promote intellectual responsibility. It emphasizes truthfulness, justice, anti-racism, and public beneficence in genetic research.

    More Related Videos

    Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
    05:53

    Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

    Published on: June 21, 2018

    10.2K
    Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains
    06:18

    Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains

    Published on: November 30, 2021

    3.9K

    Related Experiment Videos

    Last Updated: Jul 15, 2025

    Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
    09:34

    Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

    Published on: April 4, 2018

    33.8K
    Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
    05:53

    Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

    Published on: June 21, 2018

    10.2K
    Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains
    06:18

    Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains

    Published on: November 30, 2021

    3.9K

    Area of Science:

    • Genetics
    • Bioethics
    • Sociology

    Background:

    • Genetic variation patterns are used to infer genetic ancestry for diverse research.
    • Genetic ancestry research has significant societal implications beyond intellectual inquiry.
    • Existing ethical guidelines may not fully address the nuances of genetic ancestry research.

    Purpose of the Study:

    • To present a virtue ethics framework for researchers utilizing genetic ancestry.
    • To foster researchers' capacity to address ethical dimensions in their work.
    • To guide researchers in aligning their practices with ethical principles.

    Main Methods:

    • The framework is grounded in virtue ethics, focusing on character and capacity building.
    • It proposes an overarching principle of intellectual freedom and responsibility.
    • Four key principles are defined: truthfulness, justice and fairness, anti-racism, and public beneficence.

    Main Results:

    • The framework identifies common research practices that may infringe ethical principles.
    • A step-by-step process and rules of thumb are provided for aligning research with principles.
    • A worked case illustrates the application of the ethical framework.

    Conclusions:

    • Researchers need support to effectively implement the proposed ethical framework.
    • Adopting this framework can lead to more responsible and ethically sound genetic ancestry research.
    • The framework aims to enhance the ethical conduct of genetic research with societal impact.