FRUCTOSAMINE VALUES IN MONITORING COMPENSATION AND EFFICACY OF DIABETES MELLITUS TREATMENT

Aim: The relevance of the study is determined by the objective of finding an optimal type of diagnostics of carbohydrate metabolism, that would assess the condition of a diabetic patient undergoing treatment. The purpose of the study is to create a model for monitoring the efficacy of diabetes mellitus treatment by determining the fructosamine levels.

Materials and Methods: The methods for investigating the highlighted issue are clinical examination and laboratory diagnosis of diabetic patients to measure the state of carbon metabolism using ion-exchange chromatography to determine glycated haemoglobin levels and an automatic colorimetric method to determine fructosamine levels.

Results: The study presents certain values of fructosamine over the level of changes in the state of patients with diabetes mellitus, reflecting the progress from the treatment in the compensation of carbohydrate metabolism, which allows creating a model of diagnostic values of the fructosamine levels, according to which the efficacy of treatment of diabetes mellitus, the state of progress of the disease in its compensation or decompensation are determined at a qualitative level.

Conclusions: This allows for the timely adaptive corrective therapeutic and preventive measures to be carried out by medical personnel, who, using values, will monitor the efficacy of treatment in each patient once every three weeks, as this will determine the influence of the type of conducted treatment or other factors aimed at compensating for pathogenetic and clinical manifestations of the disease, which makes the identified fructosamine criteria an important component in the treatment of diabetes mellitus, and indirectly allows to improve the life quality of this patient population, thus bringing a practical solution to the challenge facing the healthcare sector.