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Risk Factors Associated With Postoperative Cardiac Events Following Total Hip and Knee Arthroplasty
Shivan N Chokshi1, Vanessa Liu1, William M Weiss2
1John Sealy School of Medicine, The University of Texas Medical Branch, Galveston, Texas.
Insights
Patients undergoing total joint arthroplasty face increased cardiac risks. Pre-existing conditions like prior myocardial infarction and renal insufficiency significantly elevate the likelihood of adverse cardiac events post-surgery.
Area of Science:
- Orthopedic Surgery
- Cardiology
- Public Health
Background:
- Adverse cardiac events are a concern following total joint arthroplasty.
- Investigating cardiac risk factors is crucial for patient outcomes.
Purpose of the Study:
- To determine the prevalence of adverse cardiac events after total hip arthroplasty (THA) and total knee arthroplasty (TKA).
- To analyze specific risk factors associated with perioperative cardiac complications.
Main Methods:
- Utilized a large national database for data extraction.
- Analyzed 80,544 THA and 112,531 TKA patients.
- Performed chi-squared and multivariate analyses on cardiac risk factors including diabetes, renal insufficiency, prior MI, hypertension, and cerebrovascular disease.
Main Results:
- 34% of THA and 52% of TKA patients had at least one cardiac risk factor.
- At-risk patients showed significantly higher odds of troponin elevation, myocardial infarction (MI), and heart failure within 30 days.
- Prior MI was the strongest predictor for troponin elevation and MI; renal insufficiency for heart failure.
Conclusions:
- Risk stratification is essential for minimizing adverse outcomes in orthopedic surgery.
- Identifying and considering patient risk factors before joint arthroplasty is critical.
Background:
This study investigated the prevalence of adverse cardiac events following a total joint arthroplasty and subsequently analyzed risk factors that may increase the likelihood of these events.
Methods:
Data for this study were extracted from a large national database. Chi-squared analyses and multivariate modelings were performed to determine the risk factors associated with 30-day perioperative troponin elevation, myocardial infarction (MI), and heart failure. We identified 80,544 total hip arthroplasty (THA) patients and 112,531 total knee arthroplasty (TKA) patients and analyzed the following cardiac risk factors: diabetes, renal insufficiency, prior MI, hypertension, and cerebrovascular disease.
Results:
There were 34% of THA patients and 52% of TKA patients who had at least one of the studied risk factors. At-risk THA patients had 2.2, 5.9, and 5.3 times the odds of troponin elevation, MI, and postoperative heart failure, respectively, within 1 month compared to the control group (P < .0001). The TKA group had 2.9, 5.3, and 5.9 times the odds of troponin elevation, MI, and postoperative heart failure within 1 month compared to the control group (P < .0001). For both procedures, prior MI had the highest odds of resulting in perioperative troponin elevation and MI. Renal insufficiency had the highest odds of resulting in perioperative heart failure.
Conclusions:
Risk stratification for postoperative complications in orthopedic surgery is important to minimize adverse outcomes. This study highlights the need for consideration of risk factors prior to joint arthroplasty surgery.
Level Of Evidence:
Level III, Prognostic.
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